Scientists Uncover Fat-Burning Protein Switch

Obese Man Tape Measure Fat
Researchers at CNIO have discovered that blocking the mitochondrial protein MCJ in brown fat increases heat production and leads to weight loss in obese mice, offering protection against obesity-related diseases like diabetes. This finding highlights MCJ as a potential therapeutic target for treating obesity and its associated health risks.

A new study uncovers a novel mechanism through which brown fat is transformed into heat, offering protection against obesity-related diseases.

Obesity affects 650 million people worldwide and significantly contributes to the development of cardiometabolic diseases and increases the risk of cancer. Guadalupe Sabio, head of the Organ Crosstalk in Metabolic Diseases Group at the National Cancer Research Centre (CNIO), and Cintia Folgueira, from CNIO and the National Centre…

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