On the eve of 2020, the world was rocked by news of an emerging epidemic. In the coming months, as scientists scrambled for answers, pandemonium swept like waves across the borders of six continents.1
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Five years later, we can tell the tale of using the tools of science, we were able to turn the tide on SARS-CoV-2 and, in the process, rewrite the playbook on pandemic preparedness. Through unprecedented global collaboration, innovative technology, adaptive clinical trials, sensible regulatory revisions, and extraordinary funding, a polished vaccine R&D program came into existence. Based on the principles of expedience, adaptability, and data-driven precision, today’s vaccine R&D is now faster, safer, and more resilient to future health threats.