ISGE: Reproductive Steroids and Affective Disorders

RESEARCHERS in the USA have expanded understanding of the pathophysiology behind reproductive mood disorders, according to a research abstract presented at the 2026 Annual Congress of the International Society of Gynecological Endocrinology.

Affective Disorders

Affective disorders are a leading source of disease burden worldwide and significant causes of morbidity and mortality, with the ability to shorten a lifespan by more than a decade.

They account for more than 200 billion USD annually in direct and indirect costs in the USA.

Premenstrual Dysphoric Disorder

Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome that occurs during the luteal phase of the menstrual cycle.

Symptoms can include depression, anxiety, concentration problems, and fatigue.

There are currently very few…

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