A large observational analysis has failed to detect any clinically meaningful benefit of statin use on bone mineral density (BMD), a team of Canadian and U.S. researchers reported.
The finding is from a clinical registry of 22,393 individuals who underwent dual-energy x-ray absorptiometry (DEXA) scans and clarifies whether or not statins may lower risk for osteoporosis, noted lead author William Leslie, of the University of Manitoba in Winnipeg, Canada, and colleagues.
“In this large clinical registry of individuals undergoing initial and repeat assessment with [DEXA], there was inconsistent and largely negative evidence for statin use affecting initial total hip BMD or rate of BMD loss during follow-up,” the group wrote. The study was published May 29 in the Journal of Bone and Mineral Research.
Statins are among…