By reducing the diameter of the structural components to less than 1 µm, TAL-based nanowaveguides use light diffraction to achieve resolutions that significantly exceed 200 line pairs per millimeter (lp/mm)—a high level of image resolution, even under white Lambertian illumination. It surpasses modern fiber-optic systems that depend on total internal reflection, which restricts its maximum resolution to the size of the fiber itself—and the optimal performance achieved in optical fiber bundles for light localization typically results in a resolution of about 4 µm. But our new nanowaveguides can achieve narrow localization spots far better than 2.5 µm, which enables sharper, more precise image guidance, and makes it suitable for high-performance applications.