CHILDHOOD food allergy risk begins early, shaped by a complex interaction of genetic, environmental, and clinical factors, according to a large systematic review and meta-analysis. Analysing data from 190 studies involving approximately 2.8 million participants across 40 countries, researchers identified the most robust predictors of food allergy development before 6 years of age, offering new insights to guide prevention strategies and clinical decision-making.
Global Data Clarify Drivers of Childhood Food Allergy
Food allergy incidence confirmed by oral food challenge was estimated at 4.7%, highlighting the growing global burden of allergic disease in early life. The investigators assessed 342 potential risk factors, using multivariable analyses and rigorous evidence grading to determine which were…