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'Groundbreaking' Potential Lupus Cure Sends Patients into Remission, Allowing Dreams to Be Fulfilled

A pioneering NHS trial in the UK used genetically modified T-cell therapy to treat lupus. Five patients achieved complete remission and no longer require medication to manage the condition. The treatment aims to reset the immune system for this chronic autoimmune disease.

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New reports confirm five patients in a UK trial achieved complete remission via CAR T-cell therapy.

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  1. CAR T-cell Therapy Trial Puts Lupus Patients into Remission

    A pioneering NHS trial in the UK used genetically modified T-cell therapy to treat lupus. Five patients achieved complete remission and no longer require medication to manage the condition. The treatment aims to reset the immune system for this chronic autoimmune disease.

    What's confirmed:

    • A UK trial of CAR T-cell therapy sent five lupus patients into remission.
    • The therapy genetically modifies a person's T-cells to treat the autoimmune disease.
    • Patients in the trial have not needed medication to manage their condition.
    • The therapy was originally developed for cancer treatment.

    Still unconfirmed:

    • One previously bedridden woman fulfilled a dream of skiing for the first time following the treatment.
    • Lupus affects 1.5 million people in the United States.
    • The therapy could offer a cure for the chronic autoimmune disease.
    confidence 90%