Targeted genomic integration and rearrangement using prime assembly — Live Feedhttps://www.live-feeds.com/feed/targeted-genomic-integration-and-rearrangement-using-prime-assemblyContinuously updated, source-cited coverage. Boston Children's Team Develops Prime Assembly for Large DNA Insertionshttps://www.live-feeds.com/feed/targeted-genomic-integration-and-rearrangement-using-prime-assemblyhttps://www.live-feeds.com/feed/targeted-genomic-integration-and-rearrangement-using-prime-assembly#u80131Tue, 22 Sep 2026 14:05:46 +0000A research team led by Boston Children's Hospital has developed a gene-editing method called prime assembly. This technique allows for the precise insertion of large DNA sequences and the simultaneous correction of multiple mutations. By enabling long and targeted genomic integration and rearrangement, the method expands the capability of current gene-editing tools to handle more complex genetic modifications than previously possible.Why it mattersPrecise insertion of large genetic sequences is a significant challenge in genomic medicine. This development provides a mechanism to fix multi