https://www.live-feeds.com/feed/three-deaths-in-car-t-trials-prompt-halt-by-novartis-bristol-myers-programs-also-pausedContinuously updated, source-cited coverage. https://www.live-feeds.com/feed/three-deaths-in-car-t-trials-prompt-halt-by-novartis-bristol-myers-programs-also-pausedhttps://www.live-feeds.com/feed/three-deaths-in-car-t-trials-prompt-halt-by-novartis-bristol-myers-programs-also-paused#u55652Thu, 03 Sep 2026 12:31:31 +0000Novartis paused eight clinical trials of its rapcabtagene autoleucel (rap-cel) therapy after three patients died from immune effector cell-associated hemophagocytic syndrome (IEC-HS). This rare, life-threatening immune response occurred during tests for neurological and autoimmune diseases, including rheumatoid arthritis and lupus. Bristol Myers Squibb also halted its similar CAR-T programs following separate safety signals. Both companies informed Endpoints News of the pauses to review safety issues. Wall Street analysts suggest that stricter manufacturing and enrollment protocols may be nece https://www.live-feeds.com/feed/three-deaths-in-car-t-trials-prompt-halt-by-novartis-bristol-myers-programs-also-pausedhttps://www.live-feeds.com/feed/three-deaths-in-car-t-trials-prompt-halt-by-novartis-bristol-myers-programs-also-paused#u54354Wed, 02 Sep 2026 04:06:15 +0000Novartis has paused its autoimmune CAR-T cell therapy trials due to three patient deaths. The trials were halted as a precautionary measure after severe immune reactions linked to the therapy were reported. Bristol Myers Squibb also paused its CAR-T trials. The CAR-T cell therapy is an experimental treatment that involves removing T cells from a patient's blood, modifying them to recognize cancer cells, and reinfusing them back into the patient.Why it mattersThe halted trials are part of a larger investigation into the safety of CAR-T cell therapies. CAR-T cell therapies have shown promis