Improving the genetic circuits in eukaryotic protein production systems—like human cell lines or Chinese hamster ovaries—has the potential to enhance their value so they may offer not only their own inherent benefits, but also the higher protein production and lower production costs associated with such prokaryotic systems as Escherichia coli. The protein-responsive upregulating riboswitches (ON-riboswitches) … Read more
Broadcast Date: Wednesday, April 9, 2025 Time: 8:00 am PT, 11:00 am ET, 17:00 CEST Product safety and efficacy is an integral part of conversations about the potential of cell and gene therapies, particularly when compared to traditional drug products like small molecules. The presence of visible and subvisible particles is a major indicator of … Read more
View eBook Messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that carries the instructions from DNA to create specific proteins. The main applications for mRNA include immunotherapy, protein replacement therapy, genvomic editing, and regenerative medicine therapy, and notably vaccines. Lipid nanoparticles (LNPs) are the most common drug delivery systems to encapsulate, protect, and … Read more