Unravelling the mode of action of the Tres Cantos Antimalarial Set (TCAMS): investigating the mechanism of potent antimalarial compounds potentially targeting the human serotonin receptor | Malaria Journal
Characterization of the IC50 values and evaluation of the cytotoxicity of the compounds in the TCAMS library The IC50 values for each compound were determined in asynchronous cultures of P. falciparum 3D7 exposed to various concentrations of the test compounds (0.0019–2 μM). Parasitaemia was assessed by flow cytometry via a double-labelling technique: SYBR Green-labelled DNA and … Read more