A mid-season analysis published by investigators in The Lancet reveals a significant impact of vaccination in reducing hospital admissions linked to respiratory syncytial virus (RSV), underscoring the importance of RSV immunization for older adults.1 Image credit: kitsawet | stock.adobe.com RSV can cause severe outcomes for high-risk individuals, including those aged 75 years and older and … Read more
In patients with chronic kidney disease (CKD), there are negative associations between the sodium (Na-Cl) cotransporter (NCC) and its phosphorylation (pNCC) in urinary extracellular vesicles (uEVs) and plasma potassium, according to data published in Nephrology. This finding suggests that the mechanism at play is distinct from the overall kidney function, according to the investigators, and … Read more
In an interview with Pharmacy Times®, Elaina Rosario, PharmD, CPh, BCACP, CDCES, clinical pharmacy coordinator, ambulatory care from Baptist Health, discussed the role of glucagon-like peptide-1 (GLP-1) receptor agonists in diabetes management. Image credit: mingnimit | stock.adobe.com Rosario shares how GLP-1s mimic the incretin hormone, leading to increased insulin secretion, suppressed glucagon, slowed gastric emptying, … Read more
When used to prevent hepatitis A virus (HAV) via surface transmission, only 2 aldehyde-based surface disinfectants demonstrated a reduction in viral titer below the limit of detection, according to the authors of a new study. These findings have strong implications for evidence-based hygiene guideline recommendations to reduce the transmission of HAV, according to the investigators.1 … Read more
The current minimum vitamin B12 recommendations may be insufficient for older adults, as new research published by investigators in Annals of Neurology reveals that cognitive impairment was linked to levels within the ‘normal range,’ with the presence of white matter damage and slower cognitive processing.1,2 Image credit: Creative Habits | stock.adobe.com Vitamin B12 is crucial … Read more
In the first trial of a sodium-glucose cotransporter-2 (SGLT2) inhibitor for valvular disease, investigators found that patients with heart failure who took dapagliflozin (Farxiga; AstraZeneca) after undergoing transcatheter aortic valve replacement (TAVR) were significantly less likely to die or experience worsening heart failure at 1 year compared with patients who did not take the medication.1 … Read more
New data presented at the American College of Cardiology 2025 Scientific Session demonstrate that at 3 months of follow-up, patients hospitalized for a serious heart attack who were treated with rivaroxaban (Xarelto; Johnson & Johnson) for a blood clot in the left ventricle (LV) did as well as similar patients treated with warfarin (Jantoven; Upsher-Smith).1 … Read more
Patients with active cancer who developed a blood clot or venous thromboembolism (VTE) and who were treated with blood-thinning medication for at least 6 months followed by an additional 12 months of low-dose apixaban (Eliquis; Bristol Myers Squibb, Pfizer) experienced similar recurrences of VTE and less bleeding compared to those who received a full dose … Read more
Research published in The Lancet Gastroenterology & Hepatology found that a newly developed hepatitis B core-related antigen (HBcrAg) rapid diagnostic test (RDT) has potential in detecting hepatitis B virus (HBV) DNA concentrations in women who should be prioritized for antiviral prophylaxis. The authors noted their optimism in this method an an alternative for timely identification of … Read more
Both glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter 2 (SGLT2) inhibitors offer significant cardiovascular (CV) benefits for patients with diabetes, but the optimal choice depends on individual patient factors. While GLP-1 receptor agonists provide superior stroke prevention, weight loss, and glycemic control, SGLT2 inhibitors excel in heart failure management, CV death reduction, and renal … Read more