Introduction
Cardiovascular disease is the leading cause of mortality worldwide and coronary heart disease is one of the well-known and widely studied diseases.1 The full name for coronary heart disease(CHD) is coronary atherosclerotic heart disease.2 Atherosclerosis is a chronic inflammatory disease that is the main cause of heart attacks.2 Atherosclerosis accounts for more than 15% of deaths worldwide.3 Inflammation is an important factor in coronary artery disease and atherosclerosis.4 Chronic inflammation of the coronary artery wall driven by innate and adaptive immune system activation can lead to plaque rupture and thrombus formation.5 Cytokines, such as IL-1, IL-18, and IL-6, are involved in the formation of atherosclerosis by stimulating the movement of cells to the site of inflammation.6 Diseases, such as…