The findings could lead to more tailored treatments for cardiovascular disease.
Scientists at the National Institutes of Health (NIH) have achieved a critical milestone in understanding the mechanisms behind the accumulation of “bad” cholesterol, or low-density lipoprotein cholesterol (LDL-C), in the body. For the first time, researchers have demonstrated how the primary structural protein in LDL interacts with its receptor, initiating the process of LDL clearance from the bloodstream. They also identified the consequences of disruptions in this…