No EoE-Esophageal Cancer Link Found in Large US Study

TOPLINE:

Eosinophilic esophagitis (EoE) is not associated with the development of esophageal cancer in privately insured US adults younger than 65 years.

METHODOLOGY:

  • Because chronic inflammation is associated with several cancers, but some studies suggest that allergic inflammation, like that of EoE, might offer a protective benefit, researchers examined whether EoE is linked with esophageal cancer.
  • For their case-control study, researchers analyzed 2009-2022 data on 5562 commercially insured patients aged 18-64 years (median age, 58.8 years) with esophageal cancer. Patients were matched to 55,620 control individuals without the condition by age and amount of time in the health plan.
  • All participants were required to have at least 2 years of continuous healthcare coverage before the index date, defined as the date of the…

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