Many Early-Onset Cancers Increasing, Particularly in Women

Rates of certain cancers in the United States — including breast, colorectal, and thyroid cancers — increased between 2010 and 2019 among patients aged less than 50 years, while overall cancer incidence and mortality rates did not increase, a new study found.  Among the more than two million cases of early-onset cancer diagnosed during this … Read more

No Barrett’s Survival Benefit With Regular Surveillance

SAN DIEGO—Gastroenterologists have debated the best course of action for patients with Barrett’s esophagus for decades. Which is better for detecting early malignancy and preventing progression to esophageal adenocarcinoma (EAC) — surveillance endoscopy at regular intervals or only when symptoms occur? Does one offer a better chance of survival than the other? Now, researchers who … Read more

Cancer Deaths Fall in Europe, but Not Across All Types

Cancer statistics in Europe are encouraging: Between 1989 and 2025, nearly 7 million deaths were averted in the European Union (EU), including over 373,000 from breast cancer. This finding emerged from a study recently published in the Annals of Oncology by a team of researchers led by Carlo La Vecchia from the University of Milan … Read more

ACG Issues First Guidance on Gastric Premalignant Conditions

The American College of Gastroenterology (ACG) has issued its first clinical practice guideline on the diagnosis and management of gastric premalignant conditions (GPMCs) including atrophic gastritis, gastric intestinal metaplasia, dysplasia, and certain gastric epithelial polyps, all of which have an increased risk of progressing to gastric cancer. The guideline was published online on March 12 … Read more

Candida Associated With Esophageal Cancer Risk in Achalasia

TOPLINE: Esophageal Candida infection is linked to an 8.2-fold increased risk for esophageal cancer in patients with achalasia, according to results of a retrospective cohort study. Older age at diagnosis and male sex were also associated with an increased risk. METHODOLOGY: Researchers conducted a study in of 234 patients with achalasia between January 1980 and … Read more

No EoE-Esophageal Cancer Link Found in Large US Study

TOPLINE: Eosinophilic esophagitis (EoE) is not associated with the development of esophageal cancer in privately insured US adults younger than 65 years. METHODOLOGY: Because chronic inflammation is associated with several cancers, but some studies suggest that allergic inflammation, like that of EoE, might offer a protective benefit, researchers examined whether EoE is linked with esophageal … Read more