Hippocampal functional radiomic features for identify the cognitively

Introduction

Low-back-related leg pain (LBLP) is one of the most common variations of low back pain. Individuals commonly experience pain that radiates to the leg, and it is believed to be associated with the severity of disease, increased disability, prolonged recovery, and higher health-related costs. Several studies have shown that chronic pain is associated with cognitive impairment.1,2 This decline in cognitive function has also been observed in patients with LBLP and has a negative impact on their quality of life and ability to maintain employment.3–5

Chronic pain patients with cognitive impairment may exhibit executive function deficits, particularly on working memory and emotional control subscales.6 A recent study has suggested that abnormalities of…

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