Investigators Find Causal Link Between Apolipoprotein A-I and COPD

Investigators established a causal link between apolipoprotein A-I (apoA-I) and chronic obstructive pulmonary disease (COPD), according to results of a study published in International Journal of Chronic Obstructive Pulmonary Disease. The authors of the study found a potential link between lipid metabolism and COPD in preliminary data; therefore, in this study, the investigators used a Mendelian randomization to analyze the potential causal link.1

Chronic Obstructive Pulmonary Disease, Cholesterol, ApoA-I | Image Credit: surasak | stock.adobe.com

COPD is a respiratory disease associated with demographic factors such as smoking rates and air pollution. In results from another study published in BMC Pulmonary Medicine, investigators found that cigarette smoke extract can simulate bronchial epithelial cells, which can…

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