TOPLINE:
Weekly nonpharmacologic intranasal kinetic oscillation stimulation is linked to a significant decrease in monthly headache days (MHDs) with moderate to severe intensity in patients with chronic migraine, a new study suggests.
METHODOLOGY:
- The randomized, double-blind, sham-controlled trial included 144 patients with chronic migraine across 10 centers in Germany and Finland from 2018 to 2022.
- Overall, 71 participants received active kinetic oscillation stimulation (85 Hz; 80 mbar) and 69 received sham intranasal stimulation (no vibration; 30 mbar). Both treatments were administered once weekly for 10 minutes per nostril over 6 weeks and stratified by medication overuse.
- The primary endpoint was mean change from baseline in number of MHDs with moderate to severe…