Depression is a prevalent and treatable condition that significantly impacts the quality of life among the aging US population, yet it often goes unrecognized. Selective serotonin reuptake inhibitors (SSRIs) are a class of medications that are commonly used to treat depression; however, serotonin and norepinephrine reuptake inhibitors (SNRIs) can provide further treatment options for older adults by increasing the activity of serotonin and norepinephrine in the brain.1,2
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Duloxetine (Drizalma Sprinkle; Sun Pharma) delayed-release capsules is an SNRI that received FDA approval in 2019 as the first and only approved sprinkle formulation of duloxetine. The capsules are intended to be opened, and contents can be sprinkled over applesauce, administered through a nasogastric tube,…