Post–PD-1 Data in Melanoma Offers Insight into IO Approaches

Thach-Giao Truong, MD

Medical director, Melanoma Program

Cleveland Clinic

Cleveland, OH

DISCUSSION QUESTIONS

  • How do you balance efficacy, safety, patient preferences, goals of therapy, and quality-of-life when recommending a first-line regimen?​
  • How do you select a specific IO (immunotherapy) regimen? ​
  • Do you face any barriers to use of a new IO option?​

Thach-Giao Truong, MD: How much do you consider goals of therapy and quality of life? Have people come to you with concerns like that?

Mohammad Muhsin Chisti, MD: Obviously, our goal is remission of the disease. With immunotherapy, that has been achievable. You achieve a similar goal [when] selecting one of those doublet immunotherapy regimens.

Truong: I don’t know if you are familiar with the [SWOG Cancer Research Network] S1616 trial [NCT03033576], looking at…

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