Scientists Discover Brain’s “Stop Eating” Switch

Neuron Illustration
Columbia scientists discovered specialized brainstem neurons in mice that signal when to stop eating by integrating various sensory and hormonal cues. Their findings could lead to new obesity treatments by targeting these neurons to regulate food intake.

Scientists found brainstem neurons that tell mice when to stop eating, offering insights for obesity treatments.

Columbia scientists have discovered specialized neurons in the brains of mice that signal the animals to stop eating.

While many feeding circuits in the brain are known to regulate food intake, the neurons within these circuits do not make the final decision to stop eating.

The newly identified neurons, a previously unknown component of these circuits, are located in the brainstem—the oldest part of the vertebrate brain. This discovery could…

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