Dutch Field Studies Show Promise for Two Experimental Avian Flu H5N1 Vaccines

Field studies led by Wageningen University have demonstrated the efficacy of two avian flu vaccines in reducing mortality in poultry infected with the H1N1 virus, although additional experiments are required to draw accurate conclusions about the vaccines’ impact on virus transmission.

The field studies were commissioned by the Dutch Ministry of Agriculture, Fishery, Food Security, and Nature (WBVR) following laboratory studies using the two experimental vaccines. For the field studies, 1,800 layer hens on two commercial poultry farms were vaccinated in September 2023. The field trials will be completed in the third quarter of 2025.

The layers were vaccinated with one of the HVT-vector vaccines: VECTORMUNE® AI1 or VAXXITEK HVT+IBD+H52. A third group of chickens were administered the VAXXITEK HVT+IBD+H5 vaccine at day…

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