TOPLINE:
A study showed that survivors of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) had an increased risk for cardiovascular morbidity and mortality, which peaked within the first year and remained elevated for up to 7 years after the initial SJS/TEN diagnosis.
METHODOLOGY:
- A retrospective study evaluated survivors of SJS/TEN from Taiwan’s National Health Research Institute Database from 1998 to 2021.
- Researchers included 10,571 SJS/TEN survivors (mean age, 56.1 years; 50.7% women) and 105,710 matched participants without SJS/TEN for the cerebrovascular accident (CVA) analysis, and 11,084 SJS/TEN survivors (mean age, 56.6 years; 50.2% women) and 110,840 matched participants for the ischemic heart disease (IHD) analysis.
- Primary outcomes were mortality from CVA and IHD. Secondary outcomes were…