Image Credit: © M+Isolation+Photo – stock.adobe.com
A bidirectional genetic analysis revealed a possible correlation between androgenetic alopecia and depression.1 It was found that patients with depression do not have a higher risk of developing androgenetic alopecia. Conversely, patients with androgenetic alopecia are more likely to be clinically depressed.
Mendelian randomization with genome-wide association studies (GWAS) datasets occurred. The two-sample analysis used data from the Neale Lab Consortium. The alopecia dataset included 154,988 European male and female patients with 35,563 cases and 119,435 controls. The depression dataset of 484,598 was split into 27,568 cases and 457,030 controls.
To assess genetic correlation, investigators utilized the inverse variance weighted, MR-Egger regression, weighted…