In a session dedicated to new frontiers in preventing sexually transmitted infections (STIs) at the Conference on Retroviruses and Opportunistic Infections 2025, held in San Francisco, doxycycline post-exposure prophylaxis (DoxyPEP) was the primary focus of several studies whose results were shared during the session. Collectively, the studies found that, although DoxyPEP was significantly effective in preventing STIs, the initial uptake and sustained use of the treatment was subpar in areas of San Francisco and Washington D.C.
DoxyPEP Effective in Preventing Chlamydia, Gonorrhea, Syphilis
The prevention of STIs is the primary use of DoxyPEP overall. DoxyPEP can prevent STIs such as chlamydia and syphilis in those who use it consistently. A study1 presented during the session by Hyman Scott, MD, MPH, clinical research…