TOPLINE:
Among patients with active inflammatory bowel disease (IBD), those with both clinical and biochemical disease activity and two common mental disorders had a more than sixfold increased risk for adverse outcomes, including flares, glucocorticosterioid use, hospitalisations, and death.
METHODOLOGY:
- Researchers assessed the impact of psychological comorbidity and disease activity on IBD prognosis in a longitudinal follow-up study conducted between September 2014 and October 2023.
- They included 717 patients with an established IBD diagnosis (mean age, 44 years; 55.1% women; 57.3% with Crohn’s disease) who provided data on psychological health (depression and anxiety symptoms) and clinical disease activity for both Crohn’s disease and ulcerative colitis, which were assessed using established scales.
- Participants were…