Despite similar 36-week results, chemoradiation showed a statistically significant difference in QOL scores at 3 and 7 weeks vs radiation therapy alone.
Chemoradiation led to a more significant drop in quality of life (QOL) than those who received adjuvant radiation therapy alone, although both yielded a decline in QOL among patients with intermediate risk, stage I or IIA cervical cancer who were treated with initial radical hysterectomy and pelvic lymphadenectomy, according to results from the randomized phase 3 GOG-0263 trial (NCT01101451) presented at the 2025 Society of Gynecologic Oncology Annual Meeting on Women’s Cancer (SGO).1
Patient-reported mean FACT-Cx TOI QOL scores were 80.1 (SD, 15.4) with chemoradiation and 83.3 (SD, 15.4) with radiation alone at baseline; 71.4 (SD, 15.3) and 79.0 (SD, 16.4),…