For roughly one in every hundred people, food containing even the smallest amounts of gluten can deliver a gutful of hurt and pose severe risks to their health.
While a domino effect of immunological reactions can be traced back to their genetic roots, a number of contributing factors are also involved, making it difficult to map the precise chain of events that causes celiac disease.
Using transgenic mice, an international team led by scientists from McMaster University in Canada has identified a crucial role played by the very cells making up the gut’s lining, describing a major stepping stone that could lead to new therapies.
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Celiac disease is a lifelong autoimmune disorder triggered by the presence of a…