TOPLINE:
The albumin–bilirubin (ALBI) score predicted adverse outcomes such as preterm birth, intensive care unit (ICU) admission, and perinatal mortality in pregnant women with cirrhosis.
METHODOLOGY:
- This prospective, national observational cohort study was conducted using the UK Obstetric Surveillance System (UKOSS) from June 1, 2017, to November 30, 2020.
- The study identified 52 pregnant women with cirrhosis (median age, 34 years) among an estimated 2,256,366 maternities, with data collected from all 193 UK consultant-led obstetric units.
- Cirrhosis was confirmed via liver biopsy, radiological findings, or clinical/laboratory evidence.
- The ALBI score’s ability to predict adverse pregnancy outcomes was assessed using the area under the receiver operating characteristic curve (AUROC).
- The outcomes included the incidence…