Low-Dose Minoxidil for Alopecia May Not Be Safe for Patients with SLE

Devyn Zaminski

Credit: LinkedIn

New findings suggest dermatologists avoid 5 mg-per-day doses of oral minoxidil for alopecia in those with systemic lupus erythematosus (SLE) and other risk factors for pericardial side effects, or prescribe in collaboration with a cardiologist and/or rheumatologist.1

Although evidence indicates those with SLE maintain a greater risk of developing pericardial side effects due to antihypertensive oral minoxidil doses, the risk of side effects from low-dose minxoidil were acknowledged as largely unknown.2

Given this lack of data, investigators, led by Devyn Zaminski, an MD candidate from the New York University (NYU) Grossman School of Medicine, noted dermatologists may have been hesitant to prescribe it to those with SLE.

“This hesitancy may result in the underutilization of [low-dose oral…

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