New approach could treat anthrax beyond the ‘point of no return’

Anthrax, an infectious disease caused by the bacterium Bacillus anthracis, is often treatable in its early stages. But once the disease has progressed beyond the “point of no return” after just a few days, patients are almost certainly doomed.

In a new Nature Microbiologystudy, University of Pittsburgh researchers show that a cocktail of growth factors reversed would-be lethal cell damage in mice with anthrax, suggesting that this approach could be adapted for use in patients beyond the brink.

“While only a few people die from anthrax in the United States each year, there is always the concern that the bacterium could be released on a large scale as a bioweapon,” said senior author Shihui Liu, M.D., Ph.D., associate professor of medicine at the Pitt School of Medicine and member of the Aging Institute, a joint venture…

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