No significant long-term benefits found in cocoa extract for AMD

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(Image Credit: AdobeStock/kaiskynet)

An ancillary segment of the COSMOS randomized clinical trial (NCT03205202) found that cocoa extract supplementation over an extended period did not affect the overall occurrence of age-related macular degeneration (AMD) in older patients,1 according to first author William G. Christen, ScD, for the COSMOS Research Group. He is from the Division of Preventive Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston.

This large study sought to determine if daily supplementation with cocoa extract, a source of flavanols, reduces the occurrence or progression of AMD.

“Although the pathophysiology remains unclear, the consistent observation of decreased choroidal circulation in eyes with AMD2-4 supports a vascular basis for the disease and has led some investigators to…

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