Introduction
Although combined antiretroviral therapy (cART) has made significant strides in suppressing HIV replication, effectively normalizing life expectancy for people living with HIV (PLWH) to levels comparable with the general population, a complete cure for HIV remains elusive.1,2 HIV-associated neurocognitive disorders (HAND) are among the most prevalent neurological sequelae, affecting an estimated 18% to 47% of PLWH. These disorders are primarily characterized by deficits in attention, working memory, information processing speed, and fine motor skills.3,4 Such impairments continue to undermine the quality of life of individuals with HIV, impairing their ability to adhere to medication regimens, manage finances, operate vehicles, and maintain employment, thereby placing a considerable strain on both…