Fatigue and frailty, two common comorbidities of inflammatory rheumatic diseases, often receive insufficient attention in rheumatologic care settings.
Fatigue significantly reduces quality of life, while frailty is associated with numerous risks and is not limited to older adults, according to Klaus Krüger, MD, head of the St. Bonifatius Rheumatology Practice Center in Munich, Germany.
Speaking at the Rheumatism Update 2025 in Mainz, Germany, Krüger emphasized that frailty is linked to falls, fractures, increased hospitalizations, a nearly threefold higher mortality rate, and frequent infections. Christian Kneitz, MD, a rheumatologist from Schwerin, Germany, confirmed these findings.
“Fatigue is often cited as the second most debilitating manifestation after pain,” Krüger said. Approximately half of individuals…