Metabolic MRI method shows promise in Alzheimer’s cases

Deuterium metabolic imaging (DMI) was highly aligned with F-18 FDG-PET — a cornerstone of dementia diagnostics — in patients with Alzheimer’s disease in a study published on 8 April in Radiology.

The finding is a significant step forward for the emerging technique, even though it did not help differentiate participants with and without the disease, noted lead author Dr. Nikolaj Bøgh, PhD, of Aarhus University in Aarhus, Denmark, and colleagues.

“Further investigations into the use of DMI in dementia are warranted, especially once the expected developments in the technology are achieved,” the group wrote.

DMI can be performed with the same MRI scanner that supplies standard structural images, the authors explained. Prior to imaging, patients drink solutions of deuterium-labeled glucose, which is taken up by…

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