Lipidomics Reveals Common Mechanisms in PCOS, Recurrent Spontaneous Ab

Introduction

Polycystic ovary syndrome (PCOS), infertility, and recurrent spontaneous abortion (RSA) are major reproductive health challenges for women, contributing substantially to the global public health burden.1–3 Due to their high prevalence and profound impact on quality of life, these conditions have become central focuses in medical research. Recent studies have highlighted that PCOS, infertility, and RSA share common lipid metabolism abnormalities, particularly involving physiological imbalances such as insulin resistance, oxidative stress, and chronic inflammation.4–6 These factors significantly increase the risk of ovulatory disorders, abnormal embryo development, and pregnancy complications by disrupting hormone regulation, ovarian function, and…

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