Introduction
Neurodegenerative diseases (NDs), including Alzheimer’s (AD) and Parkinson’s disease (PD), are characterized by progressive neuron degeneration, primarily within the central nervous system (CNS).1 These debilitating NDs are a major global health challenge because they are growing at epidemic proportions, and have only a few treatment options.2 AD and PD are associated with different pathological characteristics in their clinical manifestations. AD is the most common ND and is characterized by progressive cognitive impairment. Such impairment is associated with the accumulation of amyloid-beta peptide (Aβ) plaques and neurofibrillary tangles formed by hyperphosphorylated tau protein in the hippocampus and cerebral cortex, which results in neuronal death…