Now an MRNA vaccine is approved in Switzerland

Swissmedic gives the RSV MRNA vaccine from Moderna approval. This is said to protect older adults from the dangerous airways, which can lead to pneumonia.

Now there is another against RSV in addition to the MRNA vaccine against Covid-19 in Switzerland.

Bild: Getty

The respiratory syncytial virus (RSV) is a highly contagious, seasonal respiratory virus. It is one of the main causes for infections of the lower respiratory tract and pneumonia. Infants are most at risk from infection with RSV. In the winter half year, RSV is the most common cause of hospitalizations.

But not only newborns are at risk. “Even older people and patients with immune deficiency can develop a serious course of illness and pneumonia, which leads to hospitalization more often,” says Stefan Kuster, chief physician infectiology at the St.Gallen cantonal hospital. In the EU, RSV causes around 160,000 hospitalization in adults annually, with 92 percent of these cases affecting people aged 65 and over. In Switzerland, the number of hospital admissions due to RSV from 2016 to 2021 was between 3000 and 6000 per year.

This week, the Swiss Remedies Institute Swissmedic has now approved a first MRNA vaccination from the manufacturer Moderna, called Mresvia. It is the first MRNA vaccine to be approved in Switzerland and the EU for a different disease than Covid-19.

The MRNA-1345 vaccine contains a MRNA sequence to the coding of a protein that is located on the surface of the virus. This protein clears the way for an penetration of the virus into the host cells. With the neutralizing antibodies created by the vaccination, the penetration of the RSV is combated.

Not to be confused with the failed mRNA vaccine for babies

In the EU, the MRNA vaccine Mresvia received approval in August 2024. The same vaccine (MRNA-1345) from Moderna had been planned for infants simply with a smaller amount of vaccine (15 or 30 μg instead of 50μg). The clinical studies on babies were stopped in the first phase of study because in some cases there were serious side effects. At MRESVIA, Moderna speaks of positive results from the phase 3 study, a global study with around 37,000 adults aged 60 and over in 22 countries. In the STudie no serious side effects were found.

Two protein-based RSV vaccinations from Pfizer (Amrysvo) and GSK (Arexvy) have been approved since summer 2024, also for older adults. ABRYSVO is also approved for pregnant women to protect their newborn children. The Federal Office of Health and the Ekif Vaccination Commission recommend these two vaccinations for adults aged 75 and over and for people with increased risk of complications from the age of 60.

ABRYSVO is recommended for pregnant women aged 18 and over in the last third of pregnancy, from October to February, when the birth date is before the end of March. “At the moment, however, there is still no cost for the RSV vaccinations from the mandatory nursing insurance,” says Stefan Kuster. The assumption of costs is currently in clarification.

Mresvia from Moderna is not approved for infants. For these there is the vaccination-like active ingredient nirvesimab with the brand name Beyfortus, which is injected in the first week after birth. This specific RSV prevention measure is successfully used in Swiss children’s hospitals. At Beyfortus, there are practically never side effects and if so, then only a redness at the injection site, as a child infectiologist explained at the beginning of the year. The baby’s monoclonal antibodies acting against RSV are injected directly into the body, which is why they work immediately and the effect does not have to be built up as in the event of a vaccination.

date: 2025-05-01 15:05:00

mRNA Vaccine Approved in Switzerland: A Comprehensive Guide

The healthcare landscape in Switzerland has recently undergone a important shift with the approval of an mRNA vaccine. This milestone marks a new era in preventative medicine for the Swiss population. but what does this really mean for you? This article breaks down the implications, benefits, potential side effects, and everything else you need to know about mRNA vaccines now available in switzerland.

Understanding mRNA Vaccines: The Science Behind the Innovation

Before diving into the specifics of the approved vaccine in Switzerland, let’s frist understand the revolutionary technology behind mRNA vaccines. Unlike conventional vaccines that use weakened or inactivated viruses, mRNA vaccines take a different approach.

here’s a breakdown:

  • mRNA (messenger RNA): This is a molecule that carries genetic instructions from DNA to the cell’s protein-making machinery.
  • How it Works: mRNA vaccines contain a synthetic strand of mRNA that instructs your cells to produce a harmless piece of a virus (typically a spike protein).
  • Immune Response: Your immune system recognizes this viral protein as foreign and starts building an immune response, including producing antibodies and activating T-cells, without ever being exposed to the actual virus.
  • No Integration with DNA: The mRNA does not enter the nucleus of your cells, where your DNA resides. It simply provides temporary instructions and is quickly broken down by the cell.

Key Advantages of mRNA Vaccines

mRNA technology offers several advantages over traditional vaccine approaches:

  • Faster Progress: mRNA vaccines can be developed and manufactured much faster than traditional vaccines, especially crucial during pandemics.
  • High Efficacy: Clinical trials have demonstrated high efficacy rates for mRNA vaccines against various diseases.
  • Adaptability: mRNA vaccines can be easily adapted to target new variants or strains of viruses.
  • No Risk of Infection: Because they don’t use live or weakened viruses, mRNA vaccines cannot cause infection.

Which mRNA Vaccine is Approved in Switzerland?

it’s important to understand which specific mRNA vaccine has received the green light in Switzerland. [Insert Name of Specific Approved Vaccine Here – Example: “Currently, [Vaccine Name – e.g., Moderna’s Spikevax] is the approved mRNA vaccine in Switzerland.”] Always refer to official sources like Swissmedic (the Swiss Agency for Therapeutic Products) for the most up-to-date and accurate data.

Swissmedic’s Role in Vaccine Approval

Swissmedic plays a crucial role in ensuring the safety and efficacy of vaccines in Switzerland. Before approving any vaccine, swissmedic conducts a thorough evaluation of all available data, including clinical trial results, manufacturing processes, and safety profiles.This rigorous process ensures that only safe and effective vaccines are made available to the public.

Eligibility and Availability of the mRNA Vaccine in Switzerland

Understanding who is eligible to receive the mRNA vaccine and how to access it is crucial. Priority groups and availability may vary depending on the epidemiological situation and the canton you reside in.

Who Should Get Vaccinated?

Generally, health authorities recommend vaccination for the following groups:

  • Older Adults: Individuals aged 65 and older are at higher risk of severe illness.
  • Individuals with Underlying Health Conditions: People with chronic illnesses such as heart disease, lung disease, diabetes, and obesity are more vulnerable.
  • Healthcare Workers: For protecting themselves and also preventing transmission within healthcare settings.
  • Othre High-Risk Groups: As defined by the Federal Office of Public Health (FOPH) and cantonal authorities.

How to Get Vaccinated in Switzerland

Vaccination programs in switzerland are typically organized at the cantonal level. Here’s a general overview of the process:

  • Check Cantonal guidelines: Each canton has its own vaccination plan and registration process. Visit your cantonal health department’s website for the most current information.
  • Registration: You may need to register online or by phone to schedule your vaccination appointment.
  • Vaccination Centers: Vaccinations are typically administered at designated vaccination centers,hospitals,or pharmacies.
  • Required Documents: Bring your health insurance card and any other identification documents required by your canton.

Potential Side Effects and Safety Profile

Like all vaccines, mRNA vaccines can cause side effects. It’s important to be aware of the common side effects and understand when to seek medical attention.

Common Side Effects

Most side effects are mild and temporary, typically lasting a day or two. common side effects include:

  • pain, redness, or swelling at the injection site
  • fatigue
  • Headache
  • Muscle aches
  • Fever
  • Chills

Rare Side Effects

Serious side effects are very rare. Though, it’s essential to be aware of them and seek immediate medical attention if they occur. [Insert information regarding rare side effects if applicable, specifically those related to the approved vaccine in Switzerland based on Swissmedic data. Example: “In extremely rare cases,mRNA vaccines have been linked to myocarditis (inflammation of the heart muscle),especially in young men. The benefits of vaccination generally outweigh the risks,but it’s important to discuss any concerns with your doctor.”]

Reporting Side Effects

It’s critically important to report any side effects you experience after vaccination to your doctor or Swissmedic. This helps monitor the safety of the vaccine and identify any potential issues.

mRNA Vaccine and Variants: Staying Protected Against New Strains

One of the key advantages of mRNA vaccines is thier ability to be quickly adapted to target emerging variants. As viruses mutate, new variants can emerge that may be more transmissible or resistant to existing vaccines. [Insert information about the approved vaccine’s efficacy against circulating variants in Switzerland. Example: “Studies are ongoing to assess the effectiveness of [Vaccine Name] against new variants. Preliminary data suggests that the vaccine provides protection against severe illness, even against some variants.”]

Booster Doses and Variant-Specific Vaccines

Booster doses might potentially be recommended to enhance protection against variants. Variant-specific vaccines are also being developed to provide more targeted immunity. Keep an eye on recommendations from Swiss health authorities regarding booster shots and updated vaccines.

Addressing Common Concerns and Misconceptions about mRNA Vaccines

It’s natural to have questions and concerns about new medical technologies like mRNA vaccines. Addressing common misconceptions is crucial for promoting informed decision-making.

Myth: mRNA vaccines Alter Your DNA

Fact: This is completely false.mRNA does not enter the nucleus of your cells and cannot integrate into your DNA. It simply provides temporary instructions for protein production and is quickly broken down by the cell.

Myth: mRNA Vaccines Cause Infertility

Fact: There is no scientific evidence to support this claim.Studies have shown that mRNA vaccines do not affect fertility in either men or women.

Myth: mRNA Vaccines Are Rushed and Not Properly Tested

Fact: mRNA vaccines have undergone rigorous clinical trials involving tens of thousands of participants. The speed of development was due to years of prior research on mRNA technology and the urgency of the pandemic,not a compromise in safety standards. Swissmedic has thoroughly reviewed all data before approving the vaccine.

the Economic Impact of mRNA Vaccine Approval in Switzerland

The approval of an mRNA vaccine in Switzerland doesn’t just impact public health; it also has significant economic implications.

Reduced Healthcare Costs

Widespread vaccination can lead to a reduction in hospitalizations and severe illness, thereby lowering healthcare costs associated with treating infectious diseases. A healthier population also contributes to a more productive workforce.

Boost to the Pharmaceutical Industry

The approval and distribution of mRNA vaccines can stimulate the pharmaceutical industry and create new jobs. Switzerland can solidify its position as a hub for pharmaceutical innovation.

Economic Recovery

by helping to control the spread of viruses, vaccination can support economic recovery by allowing businesses to reopen and operate more normally. This leads to increased economic activity and job growth.

First-Hand Experience: Stories from Vaccinated Individuals in Switzerland

Sometimes, personal accounts can offer valuable insights and reassurance. Here are fictionalized accounts based on common real-world experiences:

Maria, 72: “I was hesitant at first, but my doctor explained the benefits of the mRNA vaccine, and I decided to get vaccinated. I had a mild fever for a day, but I felt so much safer knowing I was protected. I can now visit my grandchildren without worrying so much.”

David, 35: “As a healthcare worker, I knew I needed to get vaccinated to protect myself and my patients.The vaccination process was smooth, and I only had a sore arm for a day. It’s a small price to pay for the peace of mind it provides.”

Practical Tips for a Smooth Vaccination experience

Here are some tips to help you prepare for and manage your vaccination appointment:

  • stay Informed: Keep up-to-date on the latest recommendations from Swiss health authorities.
  • Schedule Your Appointment: Register and schedule your appointment as soon as you are eligible.
  • Prepare for the Appointment: Wear loose-fitting clothing to make it easier to access your arm.
  • Stay Hydrated: Drink plenty of water before and after your vaccination.
  • Manage Side Effects: Use over-the-counter pain relievers like paracetamol to manage any mild side effects.
  • Rest: Get plenty of rest after your vaccination.
  • monitor Your Symptoms: Contact your doctor if you experience any severe or concerning symptoms.

Resources for More Information

Stay informed by consulting these reliable sources:

  • Swissmedic (Swiss Agency for Therapeutic Products): Official information on vaccine approvals and safety.
  • Federal Office of Public Health (FOPH): Public health guidelines and recommendations.
  • Cantonal Health Departments: Information on local vaccination programs and registration processes.
  • Your Doctor: Consult with your doctor to discuss any specific concerns or questions you may have.

The Future of mRNA Technology in switzerland and Beyond

The approval of an mRNA vaccine in Switzerland is just the beginning of what this revolutionary technology can offer. mRNA technology holds immense promise for the development of new vaccines and treatments for a wide range of diseases, including cancer, genetic disorders, and infectious diseases. Swiss research institutions are actively involved in exploring the possibilities of mRNA technology, perhaps leading to further breakthroughs in healthcare.

HTML table Example (WordPress styling):

Example Vaccination Schedule
Vaccine Dose 1 Dose 2 (Interval) Booster (Recommended)
[Vaccine Name] Day 0 Day 28 6 Months After Dose 2
Other Vaccine Day 0 Day 21 Optional

Disclaimer: This article provides general information and is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider for any questions you may have regarding your health or medical treatment.

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