‘Brain-Bone-Axis’ May Link Depression With Osteoporosis, Study Claims : ScienceAlert

The effects of depression may infiltrate your very bones – and conversely, your bones may send penetrating messages all the way back to your brain.

This two-way street is a captivating new field of research that could be crucial in improving patient care, especially for older adults, argue three neurologists in China.

In a new review, the authors detail the under-appreciated “bone–brain axis” theory and how this concept can help us better understand and treat a ‘silent killer‘ like osteoporosis and a complex neuropsychiatric disorder like depression.

Their conclusion is that the bone-brain axis, once considered a speculative construct, now “represents a legitimate physiological network.”

“The clinical implications are substantial and immediate,” argue the authors – Pengpeng Li from Xi’an Aerospace Hospital,…

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