PEDIATRIC obstructive sleep apnea raised influenza and COVID-19 diagnoses over five years in a U.S. TriNetX large EHR cohort study.
Pediatric Obstructive Sleep Apnea and Viral Infection Risk
Obstructive sleep apnea in children is often discussed in the context of growth, behavior, and cardiometabolic health, but emerging evidence suggests immune consequences may also matter. In a large real world cohort study using TriNetX, investigators assessed whether pediatric obstructive sleep apnea increases the likelihood of receiving subsequent diagnoses of influenza or COVID-19 over a five-year follow-up.
The analysis included children aged 2–18 years with incident obstructive sleep apnea and matched controls without obstructive sleep apnea. Each matched cohort included 539,127 children, with a mean age of 5.6 years….