NORDIC data link gastric bypass to rare, excluded stomach cancer, with risk rising after 10 years and diagnosis potentially delayed.
Long-Term Signals After Gastric Bypass
In a population-based cohort study spanning Denmark, Finland, and Sweden, investigators assessed whether gastric bypass surgery for obesity is associated with adenocarcinoma arising in the excluded stomach and whether diagnosis may be delayed due to challenges accessing the bypassed anatomy endoscopically. The cohort included 109,097 bariatric surgeries, of which 82,394 were gastric bypasses and 26,703 were other bariatric surgeries, with follow-up extending up to 44 years.
Across the full cohort, gastric non-cardia adenocarcinoma remained uncommon, occurring in 46 patients overall. However, patterns differed over time. When comparing gastric…