Cognitive Games Improve Brain Recovery After Traumatic Injury | Futurity

Computerized Cognitive Games Enhance Neuroplasticity After Traumatic Brain Injury

New research indicates that individuals with chronic traumatic brain injuries (TBI) who engage in computerized cognitive games demonstrate improved neuroplasticity and cognitive performance. These findings offer valuable insight into the brain’s remarkable capacity for recovery and self-repair.

Understanding Neuroplasticity

Neuroplasticity refers to the brain’s ability to reorganize itself by forming new neural connections throughout life. These connections are crucial for learning, processing information, and essential functions like speech, memory, and problem-solving [1]. In a healthy brain, a dense network of strong nerve fibers supports these functions. But, a traumatic brain injury can damage these fibers, reducing the efficiency of communication between neurons.

The NYU Steinhardt Study

A study conducted by researchers at NYU Steinhardt randomly assigned 17 adults (ages 24-56) with chronic TBI to either an experimental group or a control group. The experimental group participated in 40 one-hour sessions over 14 weeks using the Brain Fitness Program 2.0, a computer program designed to improve cognitive function. The program included games focused on recalling syllable sequences, differentiating sound frequencies, and remembering details from verbal stories.

Key Findings: Changes in White Matter and Cognitive Improvement

Using diffusion magnetic resonance imaging (dMRI), a technique that measures the speed and direction of water molecule travel within the brain, researchers observed significant changes in neuroplasticity within the experimental group compared to the control group. These changes were directly correlated with improvements in processing speed, attention, and working memory [2].

“This study reveals that the changes in the nerve fibers, such as increased strength and stability, were related to the improved cognitive ability in adults with a chronic brain injury,” explains Gerald Voelbel, associate professor of cognitive neuroscience at NYU Steinhardt. “This provides great evidence that the brain can change over time, even in people with a brain injury, with computer exercises that improve cognitive abilities.”

The Role of Cognitive Reserve

The brain’s ability to recover from injury is also influenced by a concept known as cognitive reserve. [3] Cognitive reserve refers to the brain’s ability to withstand damage, and is built up through factors like education and ongoing mental stimulation. A greater cognitive reserve can buffer the brain against the effects of injury, and aging.

Neuroplasticity and Recovery Mechanisms

Following a TBI, neuroplasticity enables surviving neurons to compensate for damaged areas by rerouting signals through alternative neural networks [4]. A primary mechanism driving this process is synaptic plasticity, which involves the strengthening or weakening of connections between neurons based on activity levels.

Looking Ahead

This research, published in the Journal of Neurotrauma, underscores the potential of targeted interventions, such as computerized cognitive training, to harness the brain’s natural capacity for neuroplasticity and promote functional recovery after TBI. Further research is needed to optimize these interventions and personalize treatment approaches for individuals with varying injury profiles.

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