Alberta scientists study incomplete immunologic recovery in some people with HIV who have viral suppression

CATIE news story

To better understand changes in the immune systems of ART users, a team of scientists at the University of Calgary and the Southern Alberta HIV Clinic conducted a study. The team focused on the CD4/CD8 ratio in people with HIV who had a suppressed viral load due to ART. The researchers were interested in finding factors that could help explain why some people’s CD4/CD8 ratios do not normalize despite prolonged use of ART.

The researchers analyzed health-related information collected from 2,179 people with HIV between January 1998 and June 2022 — a span of 24 years. On average, participants were in the study for a decade. According to the research team, most participants were cisgender males and White and disclosed that they were either gay/bisexual or heterosexual. The proportion of people who…

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