Posted on: 19 March 2026
Researchers in Trinity College Dublin have found that a machine learning model could help clinicians predict which people with depression are more likely to improve with digital cognitive behavioural therapy compared to antidepressant medication.
The study, led by researchers in the School of Psychology, also describes how digital cognitive behavioural therapy (CBT) can be personalised sooner than in other settings, such as face-to-face therapy. This is because it’s already digital and measurements can be built in from the start.
The study, published in the journal JAMA Network Open, analysed data from 883 adults receiving either digital CBT or antidepressant medication. The study was designed to predict early symptom change…