Rapid and precise assessment of drug sensitivity is essential for optimizing chemotherapy and improving patient outcomes. However, conventional chemosensitivity tests are often slow, require large sample volumes, and struggle to handle complex biological samples.
In a study published in Biosensors and Bioelectronics, a research team led by Prof. WANG Hongzhi from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences developed a programmable plasmonic ring biosensor, MetaRing, which is capable of rapidly and accurately identifying paclitaxel sensitivity in breast cancer patients.
Researchers designed the MetaRing biosensor based on the coffee-ring effect. By carefully controlling nanoparticle concentration and evaporation temperature, the MetaRing biosensing platform…