A NEW study reports that prostate-specific antigen (PSA) levels decline rapidly following surgery for benign prostate enlargement (BPE), even among patients with elevated baseline PSA levels.
Elevated PSA in Benign Prostate Enlargement
Elevated total PSA (tPSA) is commonly associated with prostate cancer but may also occur in benign conditions such as BPE, creating diagnostic and management challenges. To better understand PSA dynamics after treatment, researchers evaluated PSA clearance following surgical intervention in men with BPE and baseline tPSA levels above 4 ng/ml.
The study included 154 men with benign prostate enlargement confirmed by imaging and biopsy. Participants were divided into three groups: 77 patients received medical therapy with tamsulosin and dutasteride (TDT), 43 underwent…