Targeted, High-dose Radiation May Improve Treatment for ‘Supermassive’ Bile Duct Tumors | News Releases

Patients with very large intrahepatic cholangiocarcinoma experienced improved outcomes when targeted, high-dose radiation was added to chemotherapy

PHILADELPHIA – Patients with supermassive intrahepatic cholangiocarcinoma (ICC) benefited from ablative radiation therapy, a treatment that is typically used to treat non-supermassive ICC, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

Cholangiocarcinoma is a rare cancer of the bile ducts, and the intrahepatic variant—which accounts for about 10% of cases—forms in the bile ducts within the liver.

While some patients with ICC can undergo curative-intent surgery, most patients have tumors that are unresectable due to their size or stage of progression.

“For patients with…

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