Nerinetide shows promise in stroke treatment meta-analysis

The Calgary Stroke Program, a joint University of Calgary and Alberta Health Services initiative at Foothills Medical Centre, has been involved with three papers published this week in The Lancet and Lancet Neurology-the ESCAPE-NEXT trial, the FRONTIER trial, and an individual patient-level meta-analysis across three trials. The studies, in collaboration with NoNO Inc., are focused on neuroprotection and ischemic stroke. While the primary trials were inconclusive, the meta-analysis reveals that the data provide important clues for future research into stroke treatment.

Dr. Michael Hill, MD, is the lead investigator on the ESCAPE-NEXT trial together with Dr. Mayank Goyal, MD, PhD, and co-investigator on the other analyses, along with other members of the Calgary Stroke Program and teams from around the…

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