Dyspnea, Cough, and Extreme Fatigue in a Hiker

Editor’s Note:The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians, but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. If you have a case that you would like to suggest for a future Case Challenge, … Read more

Beta-Blockers Show Promise in Curbing HD Progression

TOPLINE: Beta-blocker use is associated with a 34% reduction of onset in premanifest Huntington disease (preHD) and slower progression in early motor-manifest Huntington disease (mmHD), new research shows.  METHODOLOGY: In this longitudinal multicenter study, 174 beta-blocker users with preHD (mean age, 46.4 years; 66% women) were matched with 174 nonusers (mean age, 48 years; 66% … Read more